Why High Polyphenol Olive Oil is the Best Carrier for NMN Supplements

If you are part of the growing longevity community, chances are NMN (Nicotinamide Mononucleotide) is already part of your daily supplement stack. But did you know that taking NMN on its own might only be giving you half the results?

Top longevity researchers, including Dr. David Sinclair, have long highlighted that NMN requires a "partner" to unlock its full potential. That partner is a high-quality, high polyphenol olive oil. Here is the science behind why this combination is a "must-have" for your cellular health.

1. The Fuel and the Pedal: Activating Sirtuins

Think of your longevity genes (Sirtuins) like a high-performance engine.

• NMN provides the fuel (NAD+) that the engine needs to run.

• Polyphenols (specifically Oleocanthal found in Early Harvest oil) act as the gas pedal that tells the engine to start working.

Without a "Sirtuin Activator" like the polyphenols found in early-picked extra virgin olive oil, the NAD+ created by your NMN supplements may sit idle. By taking them together, you are actively "switching on" the genes responsible for DNA repair and cellular aging defense.

2. Improving Bioavailability

NMN is highly efficient, but your body’s ability to process longevity compounds improves significantly when healthy fats are present. High-phenolic olive oil acts as a biological carrier. The healthy monounsaturated fats in Early Harvest oil create the ideal environment for nutrient absorption, ensuring your supplements don't just pass through your system but actually reach your cells.

3. Combatting "Inflammaging"

One of the biggest hurdles to longevity is chronic, low-grade inflammation, often called "inflammaging." While NMN works on cellular energy, the Oleocanthal in high-polyphenol olive oil is a natural anti-inflammatory agent. Lab tests show that high-quality, early-harvest oils provide a potent antioxidant shield, reducing the oxidative stress that can hinder NMN's effectiveness.

The "Peppery" Test: Not All Olive Oils Are Equal

You won't find the necessary polyphenol levels in standard supermarket olive oil. To activate those longevity pathways, you need an oil that is:

• Harvested Early: When olives are green and at their peak antioxidant concentration.

• Lab-Certified: Verified to contain high levels of polyphenols (mg/kg). You want an extra virgin olive oil with a polyphenol count over 600mg/kg

• Fresh: Polyphenols degrade over time; freshness is non-negotiable. Look for the most recent harvest. In Europe this will be Oct-Nov 2025 for any oil you buy in 2026.

How to Take the Combination

Most biohackers recommend taking 1–2 tablespoons of high polyphenol olive oil in the morning alongside your NMN. That signature "sting" or "pepperiness" in the back of your throat? That is the Oleocanthal telling you it’s working.

At Early Harvest we have sourced the very best high polyphenol olive oils available in the UK - all with 3rd party lab certification so you can also see the levels of Oleocanthal which are key for NMN absorption and activtiation. Come check out our selection!